GW791343 trihydrochloride

Catalog No. A21204

GW791343 3Hcl is a P2X7 allosteric modulator; exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2).
Catalog Num A21204
M. Wt 483.81
Formula C20H27Cl3F2N4O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 309712-55-8
Synonyms GW 791343, GW-791343
SMILES O=C(NC1=CC(CN2CCNCC2)=CC=C1C)CNC3=CC=C(F)C(F)=C3.[H]Cl.[H]Cl.[H]Cl
GW791343 3Hcl is a P2X7 allosteric modulator; exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.67 mL 103.35 mL 206.69 mL
0.5 mM 4.13 mL 20.67 mL 41.34 mL
1 mM 2.07 mL 10.33 mL 20.67 mL
5 mM 0.41 mL 2.07 mL 4.13 mL

*The above data is based on the productmolecular weight 483.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.