Vortioxetine

Catalog No. A21266

Vortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.

Technical details

Catalog Num	A21266
M. Wt	298.45
Formula	C18H22N2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	508233-74-7
Synonyms	Lu AA 21004
SMILES	CC1=CC=C(SC2=CC=CC=C2N3CCNCC3)C(C)=C1

Biological Activity

Vortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.

Solubility *

In vitro	DMSO	29 mg/mL (97.17 mM)
	Water	Insoluble
	Ethanol	24 mg/mL (80.41 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.51 mL	167.53 mL	335.06 mL
0.5 mM	6.7 mL	33.51 mL	67.01 mL
1 mM	3.35 mL	16.75 mL	33.51 mL
5 mM	0.67 mL	3.35 mL	6.7 mL

*The above data is based on the productmolecular weight 298.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Vortioxetine

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions