Fexinidazole
Catalog No. A21274
Fexinidazole is a 5-nitroimidazole drug currently in clinical development for the treatment of human sleeping sickness (human African trypanosomiasis [HAT]), caused by infection with species of the protozoan parasite Trypanosoma brucei.
| Catalog Num | A21274 |
|---|---|
| M. Wt | 279.31 |
| Formula | C12H13N3O3S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 59729-37-2 |
| Synonyms | HOE 239 |
| SMILES | O=[N+](C1=CN=C(COC2=CC=C(SC)C=C2)N1C)[O-] |
Fexinidazole is a 5-nitroimidazole drug currently in clinical development for the treatment of human sleeping sickness (human African trypanosomiasis [HAT]), caused by infection with species of the protozoan parasite Trypanosoma brucei.
| In vitro | DMSO | 54 mg/mL (193.33 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.8 mL | 179.01 mL | 358.03 mL |
| 0.5 mM | 7.16 mL | 35.8 mL | 71.61 mL |
| 1 mM | 3.58 mL | 17.9 mL | 35.8 mL |
| 5 mM | 0.72 mL | 3.58 mL | 7.16 mL |
*The above data is based on the productmolecular weight 279.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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