AZD-5991 S-enantiomer
Catalog No. A21361
AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.
Catalog Num | A21361 |
---|---|
M. Wt | 672.26 |
Formula | C35H34ClN5O3S2 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2143061-82-7 |
Synonyms | AZD5991, AZD 5991 |
SMILES | O=C(O)C1=C(CCCOC2=C(C=CC=C3)C3=CC4=C2)C5=C(N1C)C(C6=C(C)N(C)N=C6CSCC7=NN(C)C(CS4)=C7)=C(Cl)C=C5 |
AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 14.88 mL | 74.38 mL | 148.75 mL |
0.5 mM | 2.98 mL | 14.88 mL | 29.75 mL |
1 mM | 1.49 mL | 7.44 mL | 14.88 mL |
5 mM | 0.3 mL | 1.49 mL | 2.98 mL |
*The above data is based on the productmolecular weight 672.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.