42-(2-Tetrazolyl)rapamycin

Catalog No. A21394

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.

Technical details

Catalog Num	A21394
M. Wt	966.21
Formula	C52H79N5O12
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	221877-56-1
Synonyms
SMILES	[H][C@]1(C(O[C@@]([C@@H](C[C@H]2C[C@@H](OC)[C@@H](N3N=CN=N3)CC2)C)([H])CC([C@@H](/C=C([C@@H](O)[C@H]4OC)\C)C)=O)=O)N(C(C([C@@]5(O)[C@H](C)CC[C@](C[C@@H](/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C4=O)OC)([H])O5)=O)=O)CCCC1

Biological Activity

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.35 mL	51.75 mL	103.5 mL
0.5 mM	2.07 mL	10.35 mL	20.7 mL
1 mM	1.03 mL	5.17 mL	10.35 mL
5 mM	0.21 mL	1.03 mL	2.07 mL

*The above data is based on the productmolecular weight 966.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

42-(2-Tetrazolyl)rapamycin

Technical details

Biological Activity

Preparing Stock Solutions