PHA-767491 hydrochloride
Catalog No. A21395
PHA-767491 hydrochloride is a dual Cdc7/Cdk9 inhibitor, with IC50s of 10 nM and 34 nM, respectively.
| Catalog Num | A21395 |
|---|---|
| M. Wt | 249.7 |
| Formula | C12H12ClN3O |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 942425-68-5 |
| Synonyms | PHA767491, PHA 767491, CAY-10572 hydrochloride, CAY10572, CAY 10572 |
| SMILES | O=C1C2=C(NC(C3=CC=NC=C3)=C2)CCN1.[H]Cl |
PHA-767491 hydrochloride is a dual Cdc7/Cdk9 inhibitor, with IC50s of 10 nM and 34 nM, respectively.
| In vitro (25°C) | DMSO | 24 mg/mL (96.11 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+30% PEG 300+2% Tween 80+ddH2O | 1 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.05 mL | 200.24 mL | 400.48 mL |
| 0.5 mM | 8.01 mL | 40.05 mL | 80.1 mL |
| 1 mM | 4 mL | 20.02 mL | 40.05 mL |
| 5 mM | 0.8 mL | 4 mL | 8.01 mL |
*The above data is based on the productmolecular weight 249.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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