ITI214

Catalog No. A21422

ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).
Catalog Num A21422
M. Wt 605.56
Formula C29H29FN7O5P
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1642303-38-5
Synonyms ITI 214, ITI-214
SMILES O=C(C1=C(NC2=CC=CC=C2)N(CC3=CC=C(C4=NC(F)=CC=C4)C=C3)N=C1N56)N(C)C5=N[C@@]7([H])[C@]6([H])CCC7.O=P(O)(O)O
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.51 mL 82.57 mL 165.14 mL
0.5 mM 3.3 mL 16.51 mL 33.03 mL
1 mM 1.65 mL 8.26 mL 16.51 mL
5 mM 0.33 mL 1.65 mL 3.3 mL

*The above data is based on the productmolecular weight 605.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.