INCB053914 phosphate

Catalog No. A21444

INCB053914 phosphate is an inhibitor of Pim extracted from patent WO 2017044730 A1, compound 1; has an IC50 of less than 35 nM.

Technical details

Catalog Num	A21444
M. Wt	611.51
Formula	C26H29F3N5O7P
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	2088852-47-3
Synonyms	INCB 053914, INCB-053914
SMILES	O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.OP(O)(O)=O

Biological Activity

INCB053914 phosphate is an inhibitor of Pim extracted from patent WO 2017044730 A1, compound 1; has an IC50 of less than 35 nM.

Solubility *

In vitro	DMSO	48 mg/mL (78.49 mM)
	Water
	Ethanol
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.35 mL	81.76 mL	163.53 mL
0.5 mM	3.27 mL	16.35 mL	32.71 mL
1 mM	1.64 mL	8.18 mL	16.35 mL
5 mM	0.33 mL	1.64 mL	3.27 mL

*The above data is based on the productmolecular weight 611.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

INCB053914 phosphate

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions