Y-27632
Catalog No. A21448
Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively.
- Renata Santos, .et al. Generation of inflammation-responsive astrocytes from glial progenitors derived from human pluripotent stem cells, STAR Protoc, 2022, Mar 17;3(2):101261 PMID: 35313707
| Catalog Num | A21448 |
|---|---|
| M. Wt | 247.34 |
| Formula | C14H21N3O |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 146986-50-7 |
| Synonyms | Y27632, Y 27632 |
| SMILES | O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2 |
Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.43 mL | 202.15 mL | 404.3 mL |
| 0.5 mM | 8.09 mL | 40.43 mL | 80.86 mL |
| 1 mM | 4.04 mL | 20.22 mL | 40.43 mL |
| 5 mM | 0.81 mL | 4.04 mL | 8.09 mL |
*The above data is based on the productmolecular weight 247.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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