MK-0674
Catalog No. A21558
MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S.
| Catalog Num | A21558 |
|---|---|
| M. Wt | 527.5 |
| Formula | C26H27F6N3O2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 887781-62-6 |
| Synonyms | MK0674, MK 0674 |
| SMILES | N#CC1(CC1)NC([C@H](CC(C)(C)F)N[C@@H](C2=CC=C(C3=CC=C(C=C3)[C@@H](O)C(F)F)C=C2)C(F)(F)F)=O |
MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.96 mL | 94.79 mL | 189.57 mL |
| 0.5 mM | 3.79 mL | 18.96 mL | 37.91 mL |
| 1 mM | 1.9 mL | 9.48 mL | 18.96 mL |
| 5 mM | 0.38 mL | 1.9 mL | 3.79 mL |
*The above data is based on the productmolecular weight 527.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
ADOOQ 产品质量保证
We promise all products to perform as described.