Kira8 Hydrochloride

Catalog No. A21780

Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Catalog Num A21780
M. Wt 637.58
Formula C31H30Cl2N6O3S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2250019-92-0
Synonyms AMG-18 Hydrochloride, AMG18, AMG 18; Kira-8, Kira 8
SMILES O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(C3=CC=C2)OC4=NC=CC=C4C5=NC(N[C@H]6CNCCC6)=NC=C5)=O.[H]Cl
Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.68 mL 78.42 mL 156.84 mL
0.5 mM 3.14 mL 15.68 mL 31.37 mL
1 mM 1.57 mL 7.84 mL 15.68 mL
5 mM 0.31 mL 1.57 mL 3.14 mL

*The above data is based on the productmolecular weight 637.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.