Kira8 Hydrochloride
Catalog No. A21780
Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Catalog Num | A21780 |
---|---|
M. Wt | 637.58 |
Formula | C31H30Cl2N6O3S |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2250019-92-0 |
Synonyms | AMG-18 Hydrochloride, AMG18, AMG 18; Kira-8, Kira 8 |
SMILES | O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(C3=CC=C2)OC4=NC=CC=C4C5=NC(N[C@H]6CNCCC6)=NC=C5)=O.[H]Cl |
Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 15.68 mL | 78.42 mL | 156.84 mL |
0.5 mM | 3.14 mL | 15.68 mL | 31.37 mL |
1 mM | 1.57 mL | 7.84 mL | 15.68 mL |
5 mM | 0.31 mL | 1.57 mL | 3.14 mL |
*The above data is based on the productmolecular weight 637.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.