GSK2194069

Catalog No. A21827

GSK2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS with an IC50 of 7.7 ?? 4.1 nM in an assay detecting released CoA.
Catalog Num A21827
M. Wt 428.48
Formula C25H24N4O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1332331-08-4
Synonyms GSK 2194069, GSK-2194069
SMILES O=C(N1C[C@H](CC2=NNC(N2C3=CC=C(C4=CC=C(OC=C5)C5=C4)C=C3)=O)CC1)C6CC6
GSK2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS with an IC50 of 7.7 ?? 4.1 nM in an assay detecting released CoA.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.34 mL 116.69 mL 233.38 mL
0.5 mM 4.67 mL 23.34 mL 46.68 mL
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL

*The above data is based on the productmolecular weight 428.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.