Liarozole dihydrochloride

Catalog No. A21853

Liarozole dihydrochloride (R75251; R85246) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase).
Catalog Num A21853
M. Wt 381.69
Formula C17H15Cl3N4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1883548-96-6
Synonyms R75251 dihydrochloride, R 75251, R-75251
SMILES ClC1=CC(C(C2=CC=C3N=CNC3=C2)N4C=CN=C4)=CC=C1.[H]Cl.[H]Cl
Liarozole dihydrochloride (R75251; R85246) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.2 mL 131 mL 261.99 mL
0.5 mM 5.24 mL 26.2 mL 52.4 mL
1 mM 2.62 mL 13.1 mL 26.2 mL
5 mM 0.52 mL 2.62 mL 5.24 mL

*The above data is based on the productmolecular weight 381.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.