Btk inhibitor 1 (R enantiomer)

Catalog No. A21861

Btk inhibitor 1 R enantiomer (Ibrutinib analog) (Compound 14) is a covalent and irreversible Bruton??s tyrosine kinase (BTK) inhibitor and can be used in synthesis of Ibrutinib and ibrutinib-based activity-based probes (ABPs).
Catalog Num A21861
M. Wt 386.45
Formula C22H22N6O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1022150-12-4
Synonyms Ibrutinib analog
SMILES NC1=C2C(N([C@H]3CNCCC3)N=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1
Btk inhibitor 1 R enantiomer (Ibrutinib analog) (Compound 14) is a covalent and irreversible Bruton??s tyrosine kinase (BTK) inhibitor and can be used in synthesis of Ibrutinib and ibrutinib-based activity-based probes (ABPs).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.88 mL 129.38 mL 258.77 mL
0.5 mM 5.18 mL 25.88 mL 51.75 mL
1 mM 2.59 mL 12.94 mL 25.88 mL
5 mM 0.52 mL 2.59 mL 5.18 mL

*The above data is based on the productmolecular weight 386.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.