BX471 hydrochloride

Catalog No. A21886

BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
Catalog Num A21886
M. Wt 471.35
Formula C21H25Cl2FN4O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 288262-96-4
Synonyms ZK-811752 hydrochloride,ZK811752, ZK 811752,TAK 659, TAK659
SMILES O=C(N)NC1=CC(Cl)=CC=C1OCC(N2[C@H](C)CN(CC3=CC=C(F)C=C3)CC2)=O.[H]Cl
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.22 mL 106.08 mL 212.16 mL
0.5 mM 4.24 mL 21.22 mL 42.43 mL
1 mM 2.12 mL 10.61 mL 21.22 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.