SB-269970 hydrochloride

Catalog No. A21889

SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors.

Technical details

Catalog Num	A21889
M. Wt	388.95
Formula	C18H29ClN2O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	261901-57-9
Synonyms	SB-269970A, SB269970, SB 269970
SMILES	OC1=CC=CC(S(=O)(N2[C@@H](CCN3CCC(C)CC3)CCC2)=O)=C1.[H]Cl

Biological Activity

SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors.

Solubility *

In vitro (25°C)	DMSO	11 mg/mL (28.28 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.71 mL	128.55 mL	257.1 mL
0.5 mM	5.14 mL	25.71 mL	51.42 mL
1 mM	2.57 mL	12.86 mL	25.71 mL
5 mM	0.51 mL	2.57 mL	5.14 mL

*The above data is based on the productmolecular weight 388.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

SB-269970 hydrochloride

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions