MSI-1436 lactate

Catalog No. A21929

MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).

Technical details

Catalog Num	A21929
M. Wt	1000.17
Formula	C37H72N4O5S . 7/2C3H6O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1309370-86-2
Synonyms	Trodusquemine lactate; Aminosterol-1436 lactate, MSI 1436, MSI1436
SMILES	NCCCNCCCCNCCCN[C@@H]1C[C@@](C[C@@H](O)[C@]2([H])[C@]3([H])CC[C@@]4(C)[C@@]2([H])CC[C@@]4([C@H](C)CC[C@@H](OS(=O)(O)=O)C(C)C)[H])([H])[C@]3(C)CC1.O=C(O)C(C)O.[3.5]

Biological Activity

MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10 mL	49.99 mL	99.98 mL
0.5 mM	2 mL	10 mL	20 mL
1 mM	1 mL	5 mL	10 mL
5 mM	0.2 mL	1 mL	2 mL

*The above data is based on the productmolecular weight 1000.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

MSI-1436 lactate

Technical details

Biological Activity

Preparing Stock Solutions