(R)-MG-132

Catalog No. A21980

(R)-MG-132 ((S,R,S)-(-)-MG-132) is the enantiomer of MG-132. (R)-MG-132 is a proteasome inhibitor with weaker cell cytotoxicity than MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.

Technical details

Catalog Num	A21980
M. Wt	475.62
Formula	C26H41N3O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1211877-36-9
Synonyms	(S,R,S)-(-)-MG-132
SMILES	CC(C)C[C@H](C(N)=O)N(C([C@H](CC(C)C)NC(OCC1=CC=CC=C1)=O)=O)[C@H](C=O)CC(C)C

Biological Activity

Solubility *

In vitro (25°C)	DMSO	77 mg/mL (161.89 mM)
	Water	Insoluble
	Ethanol	22 mg/mL
In vivo	4% DMSO+30% PEG 300+20% propylene glycol+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.03 mL	105.13 mL	210.25 mL
0.5 mM	4.21 mL	21.03 mL	42.05 mL
1 mM	2.1 mL	10.51 mL	21.03 mL
5 mM	0.42 mL	2.1 mL	4.21 mL

*The above data is based on the productmolecular weight 475.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

(R)-MG-132

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions