APX-115 free base
Catalog No. A22055
APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively.
| Catalog Num | A22055 |
|---|---|
| M. Wt | 279.34 |
| Formula | C17H17N3O |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1270084-92-8 |
| Synonyms | Ewha-18278 free base |
| SMILES | OC1=C(CCC)C(C2=CC=CC=C2)=NN1C3=NC=CC=C3 |
APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.8 mL | 178.99 mL | 357.99 mL |
| 0.5 mM | 7.16 mL | 35.8 mL | 71.6 mL |
| 1 mM | 3.58 mL | 17.9 mL | 35.8 mL |
| 5 mM | 0.72 mL | 3.58 mL | 7.16 mL |
*The above data is based on the productmolecular weight 279.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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