SC-43
Catalog No. A22295
SC-43, a Sorafenib derivative, is a potent and orally active SHP-1 (PTPN6) agonist. SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis. SC-43 has anti-fibrotic and anticancer effects.
| Catalog Num | A22295 |
|---|---|
| M. Wt | 431.8 |
| Formula | C21H13ClF3N3O2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1400989-25-4 |
| Synonyms | |
| SMILES | O=C(NC1=CC=CC(OC2=CC=C(C#N)C=C2)=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3 |
SC-43, a Sorafenib derivative, is a potent and orally active SHP-1 (PTPN6) agonist. SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis. SC-43 has anti-fibrotic and anticancer effects.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.16 mL | 115.79 mL | 231.59 mL |
| 0.5 mM | 4.63 mL | 23.16 mL | 46.32 mL |
| 1 mM | 2.32 mL | 11.58 mL | 23.16 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.63 mL |
*The above data is based on the productmolecular weight 431.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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