BTK inhibitor 1 (Compound 27)
Catalog No. A22445
BTK inhibitor 1 (compound 27) is an inhibitor of BTK with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM.
| Catalog Num | A22445 |
|---|---|
| M. Wt | 474.49 |
| Formula | C24H23FN8O2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2230724-66-8 |
| Synonyms | |
| SMILES | CC(C)(C)C1=NC(=NO1)C(=O)NCC2=C(C=C(C=C2)C3=C4C=C(NC4=NC=N3)C5=CN(N=C |
BTK inhibitor 1 (compound 27) is an inhibitor of BTK with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.08 mL | 105.38 mL | 210.75 mL |
| 0.5 mM | 4.22 mL | 21.08 mL | 42.15 mL |
| 1 mM | 2.11 mL | 10.54 mL | 21.08 mL |
| 5 mM | 0.42 mL | 2.11 mL | 4.22 mL |
*The above data is based on the productmolecular weight 474.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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