Atabecestat
Catalog No. A22605
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction.
| Catalog Num | A22605 |
|---|---|
| M. Wt | 367.4 |
| Formula | C18H14FN5OS |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1200493-78-2 |
| Synonyms | JNJ-54861911, JNJ54861911, JNJ 54861911 |
| SMILES | O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)SC=C3)=C2 |
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.22 mL | 136.09 mL | 272.18 mL |
| 0.5 mM | 5.44 mL | 27.22 mL | 54.44 mL |
| 1 mM | 2.72 mL | 13.61 mL | 27.22 mL |
| 5 mM | 0.54 mL | 2.72 mL | 5.44 mL |
*The above data is based on the productmolecular weight 367.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Contact information
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