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SRT 1720是人类SIRT1(EC1.5 = 0.16μM)相对于最接近的瑟土因同系物SIRT2和SIRT3(SIRT2:EC1.5 = 37 uM;SIRT3:EC1.5> 300 uM)的选择性激活剂。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.48 mL 212.97 mL
0.5 mM 4.26 mL 21.3 mL 42.59 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15247
作用机制 Activator (激活剂)
M. Wt 469.56
Formula C25H23N7OS
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 925434-55-5
Synonyms SRT-1720, SRT1720
SMILES C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5

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