1-Azakenpaullone

目录号: A14303

GSK-3β inhibitor

1-Azakenpaullone Chemical Structure

CAS NO. 676596-65-9

1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.

库存: 现货

规格 价格 数量
2 mg
¥ 1,200.00
5 mg
¥ 2,370.00
10 mg
¥ 3,600.00
10mM * 1mL in DMSO
¥ 2,560.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.
Targets
GSK-3α GSK-3β
In vitro DMSO 66 mg/mL (201.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.47 mL 152.36 mL 304.73 mL
0.5 mM 6.09 mL 30.47 mL 60.95 mL
1 mM 3.05 mL 15.24 mL 30.47 mL
5 mM 0.61 mL 3.05 mL 6.09 mL

*The above data is based on the productmolecular weight 328.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14303
MECHANISM OF ACTION Inhibitor
M. Wt 328.16
Formula C15H10BrN3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 676596-65-9
Synonyms N/A
SMILES C1C2=C(C3=C(C=CC=N3)NC1=O)NC4=C2C=C(C=C4)Br

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