10-DEBC HCl
目录号: A13590
AKT/PKB 抑制剂
10-DEBC HCl 是一种选择性的 Akt/PKB 抑制剂。它抑制 IGF-1 刺激的 Akt 磷酸化和激活(在 2.5 μM 时完全抑制),从而抑制 mTOR、p70 S6 激酶 和 S6 核糖体蛋白 的下游激活。
AKT/PKB 抑制剂
Discription | 10-DEBC HCl is a selective inhibitor of Akt/PKB. It inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. |
---|
目录号 | A13590 |
---|---|
分子式 | C20H25ClN2O.HCl |
分子量 | 381.3 |
CAS号 | 925681-41-0 |
SMILES | CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl |
其他名称 | Akt Inhibitor X |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2