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17-AAG (KOS953)

促销

HSP90 抑制剂

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产品目录号: A10010

库存状态:中国现货中国现货

产品名 目录号 价格 数量
17-AAG 10mg A10010-10
¥ 400.00
17-AAG 50mg A10010-50
¥ 1,600.00
17-AAG 100mg A10010-100
¥ 2,500.00
17-AAG 200mg A10010-200
¥ 3,500.00
17-AAG (KOS953) 10mM * 1mL in DMSO A10010-10mM-D
¥ 820.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent. Specifically, 17-AAG binds and inhibits Hsp90.

17-AAG (KOS953)

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Chemical Information

目录号 A10010
Mechanism of action Inhibitor
分子量 585.7
化学分子式 C31H43N3O8
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 75747-14-7
Synonyms Tanespimycin, NSC330507, CP 127374, KOS-953, KOS 953
SMILES code CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
化学名称 17-(Allylamino)-17-demethoxygeldanamycin

生物活性

Description
17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent. Specifically, 17-AAG binds and inhibits Hsp90.
Targets
HSP90 (Cell-free assay)
5 nM

溶解性

Solubility (25°C)* In vitro DMSO 117 mg/mL (199.76 mM)
Water <1 mg/mL (<1 mM)
Ethanol 5 mg/mL (8.53 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.07 mL 85.37 mL 170.74mL
0.5 mM 3.41 mL 17.07 mL 34.15 mL
1 mM 1.71 mL 8.54 mL 17.07 mL
5 mM 0.34 mL 1.71 mL 3.41 mL

*The above data is based on the productmolecular weight 585.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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