2-D08

目录号: A16852

SUMO 抑制剂

2-D08

2-D08 Chemical Structure

CAS NO. 144707-18-6

2-D08是细胞可渗透的,机械上独特的蛋白质sumoylation抑制剂。在生化测定中,它也抑制Axl,IRAK4,ROS1,MLK4,GSK3β,RET,KDR和PI3Kα,IC50值分别为0.49、3.9、5.3、9.8、11、11、17和35 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,000.00
50 mg
¥ 3,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

2-D08是细胞可渗透的,机械上独特的蛋白质sumoylation抑制剂。在生化测定中,它也抑制Axl,IRAK4,ROS1,MLK4,GSK3β,RET,KDR和PI3Kα,IC50值分别为0.49、3.9、5.3、9.8、11、11、17和35 nM。
In vitro DMSO 46 mg/mL (170.22 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37 mL 185.02 mL 370.04 mL
0.5 mM 7.4 mL 37 mL 74.01 mL
1 mM 3.7 mL 18.5 mL 37 mL
5 mM 0.74 mL 3.7 mL 7.4 mL

*The above data is based on the productmolecular weight 270.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16852
作用机制 Inhibitor (抑制剂)
M. Wt 270.24
Formula C15H10O5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 144707-18-6
Synonyms 2D08
SMILES O=C1C=C(C2=CC=C(O)C(O)=C2O)OC3=CC=CC=C13

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