2-Methoxyestradiol

Name: 2-Methoxyestradiol
SKU: A10012
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A10012

Apoptotic, antiproliferative and antiangiogenic agent

2-甲氧基雌二醇是一种诱导凋亡、抗增殖和抗血管生成的药物。通过两条途径诱导 p53 诱导的凋亡：激活 p38 和 NF-κB；以及激活 JNK 和 AP-1，导致 Bcl-2 磷酸化。

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Grouped product items
规格	价格	库存
5mg	¥140.00	现货
10mg	¥175.00	现货
25mg	¥210.00	现货
50mg	¥280.00	现货
100mg	¥350.00	现货
200mg	¥525.00	现货
*10mM 1mL in DMSO**	¥175.00	现货
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Data Sheet

SDS

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生物活性

Discription

2-Methoxyestradiol is an apoptotic, antiproliferative and antiangiogenic agent. Induces p53-induced apoptosis via two pathways: activation of p38 and NF-κB; and activation of JNK and AP-1 leading to Bcl-2 phosphorylation.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10012
分子式	C19H26O3
分子量	302.4
CAS号	362-07-2
SMILES	[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(O)C(OC)=C3
其他名称	2-ME2
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	55 mg/mL (181.87 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2%DMSO+30%PEG300+5%Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.07 mL	165.34 mL	330.69 mL
0.5 mM	6.61 mL	33.07 mL	66.14 mL
1 mM	3.31 mL	16.53 mL	33.07 mL
5 mM	0.66 mL	3.31 mL	6.61 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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