3-deazaneplanocin A HCl (DZNep HCl)

目录号: A13947

EZH2 inhibitor

3-deazaneplanocin A HCl (DZNep HCl) Chemical Structure

CAS NO. 120964-45-6

3-deazaneplanocin A, also known as DZNep, is a well-known histone methyltransferase inhibitor, which disrupts polycomb-repressive complex 2 (PRC2), and induces apoptosis, while inhibiting proliferation and metastasis, in cancer cells, including acute myeloid leukemia, breast cancer and glioblastoma.

库存: 现货

规格 价格 数量
2 mg
¥ 1,500.00
5 mg
¥ 3,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

3-deazaneplanocin A, also known as DZNep, is a well-known histone methyltransferase inhibitor, which disrupts polycomb-repressive complex 2 (PRC2), and induces apoptosis, while inhibiting proliferation and metastasis, in cancer cells, including acute myeloid leukemia, breast cancer and glioblastoma.
靶点信息
S-adenosylhomocysteine hydrolase ()
50 pM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.48 mL 167.38 mL 334.75 mL
0.5 mM 6.7 mL 33.48 mL 66.95 mL
1 mM 3.35 mL 16.74 mL 33.48 mL
5 mM 0.67 mL 3.35 mL 6.7 mL

*The above data is based on the productmolecular weight 298.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13947
MECHANISM OF ACTION Inhibitor
M. Wt 298.73
Formula C12H15ClN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 120964-45-6
Synonyms DZNep, NSC 617989
SMILES C1=CN=C(C2=C1N(C=N2)[C@@H]3C=C([C@H]([C@H]3O)O)CO)N.Cl

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