4EGI-1
4EGI-1 是一种通过与 eIF4E 结合（KD 为 25 uM）来竞争性抑制 eIF4E/eIF4G 交互作用的抑制剂。
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生物活性
| Discription | 4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 uM. | ||
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产品信息
| 目录号 | A14199 |
|---|---|
| 分子式 | C18H12Cl2N4O4S |
| 分子量 | 451.28 |
| CAS号 | 315706-13-9 |
| SMILES | C1=CC=C(C(=C1)CC(=NNC2=NC(=CS2)C3=CC(=C(C=C3)Cl)Cl)C(=O)O)[N+](=O)[O-] |
| 其他名称 | 4EGI1, 4EGI 1 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 79 mg/mL (175.06 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5%DMSO+pbs | 3 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.16 mL | 110.8 mL | 221.59 mL |
| 0.5 mM | 4.43 mL | 22.16 mL | 44.32 mL |
| 1 mM | 2.22 mL | 11.08 mL | 22.16 mL |
| 5 mM | 0.44 mL | 2.22 mL | 4.43 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 315706-13-9 | 315706-13-9 供应商 | 315706-13-9 花费 | 315706-13-9 生产商 | 订购 315706-13-9 | 315706-13-9 代理商