6-Mercaptopurine Monohydrate
目录号: A15898
de novo purine synthesis 抑制剂
6-巯基嘌呤一水合物是一种广泛使用的抗白血病药物和免疫抑制剂,它通过将硫嘌呤甲基转移酶的代谢产物掺入DNA和RNA中,抑制新生嘌呤合成。
Discription | 6-Mercaptopurine Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. |
---|
目录号 | A15898 |
---|---|
分子式 | C5H6N4OS |
分子量 | 170.19 |
CAS号 | 6112-76-1 |
SMILES | C1=NC2=C(N1)C(=S)N=CN2.O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 32 mg/mL (188.02 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 58.76 mL | 293.79 mL | 587.58 mL |
0.5 mM | 11.75 mL | 58.76 mL | 117.52 mL |
1 mM | 5.88 mL | 29.38 mL | 58.76 mL |
5 mM | 1.18 mL | 5.88 mL | 11.75 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2