Daniel Gundel, .et al. , Int J Mol Sci, 2021, Feb; 22(4): 1645 PMID: 33562048
生物活性
Discription
7ACC1 selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment; inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters.
Cell Research
Cell Line
Type
Value
Description
References
产品信息
目录号
A15810
分子式
C14H15NO4
分子量
261.27
CAS号
50995-74-9
SMILES
CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)O
其他名称
DEAC, Coumarin D 1421, D 1421
储存条件
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
溶解性数据
In vitro
DMSO
45 mg/mL (172.23 mM)
Water
Insoluble
Ethanol
Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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