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7ACC1

目录号: A15810
MCT 抑制剂?€?
7ACC1 专门干扰富含乳酸的肿瘤微环境中的乳酸通量;在表达 MCT1MCT4 运输蛋白的肿瘤细胞中抑制乳酸的进入,但不抑制乳酸的排出。
Grouped product items
规格 价格 库存 数量
200mg
¥140.00
现货
1g
¥385.00
现货
10mM * 1mL in DMSO
¥175.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用7ACC1发表的1篇文献
  • Daniel Gundel, .et al. , Int J Mol Sci, 2021, Feb; 22(4): 1645 PMID: 33562048
  • 生物活性
    Discription 7ACC1 selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment; inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters.
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A15810
    分子式 C14H15NO4
    分子量 261.27
    CAS号 50995-74-9
    SMILES CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)O
    其他名称 DEAC, Coumarin D 1421, D 1421
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 45 mg/mL (172.23 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 38.27 mL 191.37 mL 382.75 mL
    0.5 mM 7.65 mL 38.27 mL 76.55 mL
    1 mM 3.83 mL 19.14 mL 38.27 mL
    5 mM 0.77 mL 3.83 mL 7.65 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

    • Calculator Reset
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