A-1210477
A-1210477 是一种强效且选择性的 MCL-1 抑制剂。A-1210477 诱导内源性凋亡的特征，并展示了对多发性骨髓瘤和非小细胞肺癌细胞系的单药杀伤作用。
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生物活性
| Discription | A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 induces the hallmarks of intrinsic apoptosis and demonstrates single agent killing of multiple myeloma and non-small cell lung cancer cell lines. | |||||
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| Cell Research |
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产品信息
| 目录号 | A15545 |
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| 分子式 | C46H55N7O7S |
| 分子量 | 850.04 |
| CAS号 | 1668553-26-1 |
| SMILES | CC1=NN(C(=C1C2=CC=CC3=C2N(C(=C3CCCOC4=CC=CC5=CC=CC=C54)C(=O)O)CCN6CCOCC6)COC7=CC=C(C=C7)N8CCN(CC8)S(=O)(=O)N(C)C)C |
| 其他名称 | A1210477 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Warmed: 3 mg/mL (3.52 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.76 mL | 58.82 mL | 117.64 mL |
| 0.5 mM | 2.35 mL | 11.76 mL | 23.53 mL |
| 1 mM | 1.18 mL | 5.88 mL | 11.76 mL |
| 5 mM | 0.24 mL | 1.18 mL | 2.35 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1668553-26-1 | 1668553-26-1 供应商 | 1668553-26-1 花费 | 1668553-26-1 生产商 | 订购 1668553-26-1 | 1668553-26-1 代理商