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A-3 Hydrochloride是PKA（cAMP依赖性蛋白激酶，Ki =4.3μM）和cGMP依赖性蛋白激酶，Ki =3.8μM，PKC（蛋白激酶C，Ki =47μM），酪蛋白激酶I和II的抑制剂， 和MLCK（肌球蛋白轻链激酶）（Ki =7.4μM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.13 mL | 155.66 mL | 311.31 mL |
| 0.5 mM | 6.23 mL | 31.13 mL | 62.26 mL |
| 1 mM | 3.11 mL | 15.57 mL | 31.13 mL |
| 5 mM | 0.62 mL | 3.11 mL | 6.23 mL |
*The above data is based on the productmolecular weight 321.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13584 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 321.22 |
| Formula | C12H14Cl2N2O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 78957-85-4 |
| SMILES | C1=CC2=C(C=CC=C2Cl)C(=C1)S(=O)(=O)NCCN.Cl |
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