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A-438079 HCl是一种竞争性P2X7受体拮抗剂（抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9）。在其他P2受体上没有活性（IC50 > 10 uM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.19 mL | 145.94 mL | 291.88 mL |
| 0.5 mM | 5.84 mL | 29.19 mL | 58.38 mL |
| 1 mM | 2.92 mL | 14.59 mL | 29.19 mL |
| 5 mM | 0.58 mL | 2.92 mL | 5.84 mL |
*The above data is based on the productmolecular weight 342.608. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12597 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 342.608 |
| Formula | C13H10Cl3N5? |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 899507-36-9 |
| Synonyms | A-438079 , A 438079, A438079, A-438079 HCl |
| SMILES | ClC1=CC=CC(C2=NN=NN2CC3=CN=CC=C3)=C1Cl.Cl |
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