A 438079 hydrochloride

Name: A 438079 hydrochloride
SKU: A14983
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A14983

P2X7 receptor 拮抗剂

1 篇发表文献

A 438079 Hcl 是一种竞争性 P2X7 受体拮抗剂（在人类重组 P2X7 细胞系中抑制 Ca2+ 流入的 pIC50 = 6.9）。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥630.00	现货
25mg	¥1,260.00	现货
50mg	¥2,135.00	现货
100mg	¥3,780.00	现货
*10mM 1mL in DMSO**	¥770.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用A 438079 hydrochloride发表的1篇文献

Zhihua Yi, .et al. , Front Pharmacol, 2018, 9: 593 PMID: 29950989

生物活性

Discription

A 438079 Hcl is a competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line).

Targets

Target	Value

产品信息

目录号	A14983
分子式	C13H10Cl3N5
分子量	342.61
CAS号	899431-18-6
SMILES	C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	55 mg/mL (160.53 mM)
	Water	55 mg/mL (160.53 mM)
	Ethanol	Warmed: 18 mg/mL (52.53 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.19 mL	145.94 mL	291.88 mL
0.5 mM	5.84 mL	29.19 mL	58.38 mL
1 mM	2.92 mL	14.59 mL	29.19 mL
5 mM	0.58 mL	2.92 mL	5.84 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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