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A 83-01


TGF-??/ALK5 抑制剂

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产品目录号: A12358


产品名 目录号 价格 数量
A 83-01 5mg A12358-5
¥ 600.00
A 83-01 10mg A12358-10
¥ 900.00
A 83-01 25mg A12358-25
¥ 1,800.00
A 83-01 50mg A12358-50
¥ 2,800.00



A83-01 is a TGF-β kinase/activin receptor like kinase (ALK5) inhibitor.

A 83-01




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 A 83-01 发表的文献 (8)
  • Onozato D, .et al. Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells, Drug Metab Dispos, 2018, Nov;46(11):1572-1580 PMID: 29615438
  • Usui T, .et al. Preparation of Human Primary Colon Tissue-Derived Organoid Using Air Liquid Interface Culture, Curr Protoc Toxicol, 2018, Feb 21;75:22.6.1-22.6.7 PMID: 29512123
  • Kondo S, .et al. Using human iPS cell-derived enterocytes as novel in vitro model for the evaluation of human intestinal mucosal damage, Inflamm Res, 2018, Dec;67(11-12):975-984 PMID: 30317465
  • Onozato D, .et al. Efficient Generation of Cynomolgus Monkey Induced Pluripotent Stem Cell-Derived Intestinal Organoids with Pharmacokinetic Functions, Stem Cells Dev, 2018, Aug 1;27(15):1033-1045 PMID: 29742964
  • Tatsuya Usui, .et al. Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture, Int J Mol Sci, 2018, Apr; 19(4): 1098 PMID: 29642386
  • Tatsuya Usui, .et al. Establishment of a dog primary prostate cancer organoid using the urine cancer stem cells, Cancer Sci, 2017, Dec; 108(12): 2383每2392 PMID: 29024204
  • Tatsuya Usui, .et al. Establishment of a novel three坼dimensional primary culture model for hippocampal neurogenesis, Physiol Rep, 2017, Jun; 5(12): e13318 PMID: 28642339
  • Tatsuya Usui, .et al. Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment, Stem Cells Int, 2016, 2016: 7053872 PMID: 28119740

Chemical Information

目录号 A12358
Mechanism of action Inhibitor
分子量 421.52
化学分子式 C25H19N5S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 909910-43-6
Synonyms A83-01, A-83-01
化学名称 3-(6-Methyl-2-pyridinyl)-N-phenyl-4?-(4-quinolinyl)-1H-pyrazole-1-carbothioamide


A83-01 is a TGF-β kinase/activin receptor like kinase (ALK5) inhibitor.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.72 mL 118.62 mL 237.24mL
0.5 mM 4.74 mL 23.72 mL 47.45 mL
1 mM 2.37 mL 11.86 mL 23.72 mL
5 mM 0.47 mL 2.37 mL 4.74 mL

*The above data is based on the productmolecular weight 421.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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