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A-889425是选择性TRPV1受体拮抗剂。A-889425阻断TRPV1通道，IC50为335 nM（大鼠）和34 nM（人）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.51 mL | 117.53 mL | 235.06 mL |
| 0.5 mM | 4.7 mL | 23.51 mL | 47.01 mL |
| 1 mM | 2.35 mL | 11.75 mL | 23.51 mL |
| 5 mM | 0.47 mL | 2.35 mL | 4.7 mL |
*The above data is based on the productmolecular weight 425.425. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13497 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 425.425 |
| Formula | C19H18F3N3O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1072921-02-8 |
| Synonyms | A889425, A 889425 |
| SMILES | CC1=C(N=CC=C1)NC(=O)C2=CCN(CC2)C3=CC=C(C=C3)S(=O)(=O)C(F)(F)F |
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