A 922500 是一种二酰基甘油酰基转移酶 1(DGAT-1)抑制剂(在人类和小鼠的 DGAT-1 上的 IC50 值分别为 7 nM 和 24 nM)。
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生物活性
| Discription | A 922500 is a diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50 values are 7 and 24 nM at human and mouse DGAT-1 respectively). |
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产品信息
| 目录号 | A11199 |
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| 分子式 | C26H24N2O4 |
| 分子量 | 428.48 |
| CAS号 | 959122-11-3 |
| SMILES | C1C[C@H]([C@@H](C1)C(=O)O)C(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)NC(=O)NC4=CC=CC=C4 |
| 其他名称 | DGAT-1 Inhibitor 4a, A-922500, A922500 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 83 mg/mL (193.7 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 15% Captisol | 19 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.34 mL | 116.69 mL | 233.38 mL |
| 0.5 mM | 4.67 mL | 23.34 mL | 46.68 mL |
| 1 mM | 2.33 mL | 11.67 mL | 23.34 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.67 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 959122-11-3 | 959122-11-3 供应商 | 959122-11-3 花费 | 959122-11-3 生产商 | 订购 959122-11-3 | 959122-11-3 代理商

















