A2A receptor antagonist 1
目录号: A12567
adenosine A2A/A1 receptor 拮抗剂
A2A 受体拮抗剂 1(CPI-444 类似物)是一种同时针对腺苷 A2A 受体和A1 受体的拮抗剂,其 K_i 值分别为 4 nM 和 264 nM。
Discription | A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively. |
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目录号 | A12567 |
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分子式 | C16H12FN5O |
分子量 | 309.3 |
CAS号 | 443103-97-7 |
SMILES | NC1=NC(C2=CC=CO2)=C3C(N(CC4=C(F)C=CC=C4)N=C3)=N1 |
其他名称 | CPI-444 analog, CPI444, CPI 444 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 60 mg/mL (193.98 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 32.33 mL | 161.66 mL | 323.31 mL |
0.5 mM | 6.47 mL | 32.33 mL | 64.66 mL |
1 mM | 3.23 mL | 16.17 mL | 32.33 mL |
5 mM | 0.65 mL | 3.23 mL | 6.47 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2