A66

目录号: A11202

PI3K 抑制剂

A66

A66 Chemical Structure

CAS NO. 1166227-08-2

A66的S对映异构体是PI 3-激酶(PIK3CA)的p110alpha亚型的有效抑制剂。无细胞试验中IC50为32 nM,作用于p110α比作用于其他I类PI3K亚型选择性高100多倍。

库存: 现货

规格 价格 数量
5 mg
¥ 850.00
10 mg
¥ 1,400.00
50 mg
¥ 4,850.00
100 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

A66的S对映异构体是PI 3-激酶(PIK3CA)的p110alpha亚型的有效抑制剂。无细胞试验中IC50为32 nM,作用于p110α比作用于其他I类PI3K亚型选择性高100多倍。
In vitro (25°C) DMSO 77 mg/mL (195.66 mM)
Water Insoluble
Ethanol 1 mg/mL (2.54 mM)
In vivo 15% Captisol 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.41 mL 127.06 mL 254.11 mL
0.5 mM 5.08 mL 25.41 mL 50.82 mL
1 mM 2.54 mL 12.71 mL 25.41 mL
5 mM 0.51 mL 2.54 mL 5.08 mL

*The above data is based on the productmolecular weight 393.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11202
作用机制 Inhibitor (抑制剂)
M. Wt 393.53
Formula C17H23N5O2S2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1166227-08-2
Synonyms A-66
SMILES CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CSC(=N3)C(C)(C)C

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