A66
目录号: A11202
PI3K 抑制剂
S-对映体A66是PI 3-激酶（PIK3CA）p110α亚型的强效抑制剂。
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生物活性
| Discription | The S-enantiomer of A66 is a potent inhibitor of the p110alpha isoform of PI 3-kinase (PIK3CA). | |||||
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产品信息
| 目录号 | A11202 |
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| 分子式 | C17H23N5O2S2 |
| 分子量 | 393.53 |
| CAS号 | 1166227-08-2 |
| SMILES | CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CSC(=N3)C(C)(C)C |
| 其他名称 | A-66 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 77 mg/mL (195.66 mM) | |
| Water | Insoluble | ||
| Ethanol | 1 mg/mL (2.54 mM) | ||
| In vivo | 15% Captisol | 7 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.41 mL | 127.06 mL | 254.11 mL |
| 0.5 mM | 5.08 mL | 25.41 mL | 50.82 mL |
| 1 mM | 2.54 mL | 12.71 mL | 25.41 mL |
| 5 mM | 0.51 mL | 2.54 mL | 5.08 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1166227-08-2 | 1166227-08-2 供应商 | 1166227-08-2 花费 | 1166227-08-2 生产商 | 订购 1166227-08-2 | 1166227-08-2 代理商