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AAF-CMK

Serine protease 抑制剂

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产品目录号: A13605

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AAF-CMK 25mg A13605-25
¥ 1,500.00
AAF-CMK 50mg A13605-50
¥ 2,500.00
AAF-CMK 100mg A13605-100
¥ 4,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome functions1, and reversibly inhibits Cln2 (TPPI).

AAF-CMK

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Chemical Information

目录号 A13605
Mechanism of action Inhibitor
分子量 453.8
化学分子式 C16H22ClN3O3CF3COOH
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 184901-82-4
Synonyms Tripeptidyl Peptidase Inhibitor II N-Ala-Ala-Phe-CMK
SMILES code C[C@@H](C(=O)NC(=O)[C@H](C)N[C@@H](CC1=CC=CC=C1)C(=O)CCl)N.C(=O)(C(F)(F)F)O
化学名称 L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-L-alaninamide, mono(trifluoroacetate)

生物活性

Description
AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome functions1, and reversibly inhibits Cln2 (TPPI).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.04 mL 110.18 mL 220.36mL
0.5 mM 4.41 mL 22.04 mL 44.07 mL
1 mM 2.2 mL 11.02 mL 22.04 mL
5 mM 0.44 mL 2.2 mL 4.41 mL

*The above data is based on the productmolecular weight 453.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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