Abaloparatide
目录号: A23072
阿巴洛帕肽(BA 058)是一种甲状旁腺激素受体1(PTHR1)类似物。阿巴洛帕肽也是一种选择性的PTHR1激活剂。阿巴洛帕肽增强了Gs/cAMP信号传导和β-arrestin的招募。阿巴洛帕肽增强了小鼠的骨形成和皮质结构。阿巴洛帕肽具有研究骨质疏松症的潜力。
Discription | Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis. |
---|
目录号 | A23072 |
---|---|
分子式 | C174H300N56O49 |
分子量 | 3960.59 |
CAS号 | 247062-33-5 |
Sequence | Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-{Aib}-Lys-Leu-His-Thr-Ala-NH2 |
Sequence shortening | AVSEHQLLHDKGKSIQDLRRRELLEKLL-{Aib}-KLHTA-NH2 |
其他名称 | BA 058; BIM 44058 |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2