Abituzumab (DI17E6) is a humanized monoclonal antibody of the IgG2 subtype that targets integrin ??V. It effectively inhibits the phosphorylation of focal adhesion kinase (FAK), Akt, and extracellular signal-regulated kinase (ERK), key signaling molecules involved in cell migration and survival. This antibody is particularly useful in cancer research applications, with a focus on studies related to prostate cancer. Abituzumab's precise targeting of integrin ??V makes it a valuable tool for investigating the role of this integrin in tumor progression and metastasis.
Abituzumab (DI17E6) is a humanized monoclonal antibody of the IgG2 subtype that targets integrin ??V. It effectively inhibits the phosphorylation of focal adhesion kinase (FAK), Akt, and extracellular signal-regulated kinase (ERK), key signaling molecules involved in cell migration and survival. This antibody is particularly useful in cancer research applications, with a focus on studies related to prostate cancer. Abituzumab's precise targeting of integrin ??V makes it a valuable tool for investigating the role of this integrin in tumor progression and metastasis.
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