ABT-199 (Venetoclax)

Name: ABT-199 (Venetoclax)
SKU: A12500
Price: 280 CNY
Rating: 5 (11 reviews)

目录号: A12500

Bcl-2 抑制剂

11 篇发表文献

ABT-199 是一种所谓的 BH3-拟态药物，旨在阻断 Bcl-2 蛋白 的功能。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥420.00	现货
50mg	¥560.00	现货
100mg	¥770.00	现货
500mg	¥2,625.00	现货
1g	¥4,130.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用ABT-199 (Venetoclax) 发表的11篇文献

Kam Pui Tam, .et al. , PLoS Pathog, 2024, Sep 26;20(9):e1012250 PMID: 39325843

Lindy Vernooij, .et al. , EJC Paediatric Oncology, 2024, 3: 100168

Tristen Wright, .et al. , Mol Cell, 2024, Apr 4;84(7):1338-1353 PMID: 38503284

Dilay Karademir, .et al. , Med Oncol, 2023, Jul 11;40(8):234 PMID: 37432531

Nageswara Rao Reddy, .et al. , Bioanalysis, 2022, Mar;14(5):253-266 PMID: 35172610

Ashlyn Parkhurst, .et al. , Cell Death Dis, 2022, Apr 28;13(4):410 PMID: 35484114

Anna L Koessinger, .et al. , Cell Death Differ, 2022, Apr 26 PMID: 35473984

Florian J Bock, .et al. , Nat Commun, 2021, Nov 12;12(1):6572 PMID: 34772930

Chauhan D, .et al. , Cell Rep, 2018, Nov 27;25(9):2354-2368.e5 PMID: 30485805

Martin Grundy, .et al. , PLoS One, 2018, 13(1): e0190682 PMID: 29298347

Joanne Dai, .et al. , J Immunol, 2018, 200 (5) 1727-1736 PMID: 29358277

生物活性

Discription

ABT-199 is a so-called BH3-mimetic drug, which is designed to block the function of the protein Bcl 2.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12500
分子式	C45H50ClN7O7S
分子量	868.44
CAS号	1257044-40-8
SMILES	CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C
其他名称	ABT199; ABT 199; GDC-0199; RG7601
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 93 mg/mL (107.08 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+50% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.51 mL	57.57 mL	115.15 mL
0.5 mM	2.3 mL	11.51 mL	23.03 mL
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 ABT-199 (Venetoclax) | ABT-199 (Venetoclax) 供应商 | ABT-199 (Venetoclax) 花费 | ABT-199 (Venetoclax) 生产商 | 订购 ABT-199 (Venetoclax) | ABT-199 (Venetoclax) 代理商 | 购买 1257044-40-8 | 1257044-40-8 供应商 | 1257044-40-8 花费 | 1257044-40-8 生产商 | 订购 1257044-40-8 | 1257044-40-8 代理商