Trusted by 10,000+ Scientists since 2006

ABT-199 (Venetoclax)


Bcl-2 抑制剂

0 Customer Reviews
产品目录号: A12500


产品名 目录号 价格 数量
ABT-199 10mg A12500-10
¥ 1,200.00
ABT-199 25mg A12500-25
¥ 2,500.00
ABT-199 50mg A12500-50
¥ 5,200.00
ABT-199 100mg A12500-100
¥ 8,000.00
ABT-199 10mM * 1mL in DMSO A12500-10mM-D
¥ 1,630.00



ABT-199 is a so-called BH3-mimetic drug, which is designed to block the function of the protein Bcl 2.

ABT-199 (Venetoclax)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 ABT-199 (Venetoclax) 发表的文献 (3)
  • Chauhan D, .et al. BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1汕 Maturation in Macrophages, Cell Rep, 2018, Nov 27;25(9):2354-2368.e5 PMID: 30485805
  • Martin Grundy, .et al. Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling, PLoS One, 2018, 13(1): e0190682 PMID: 29298347
  • Joanne Dai, .et al. Intracellular BH3 profiling reveals shifts in anti-apoptotic dependency in B-cell maturation and activation, J Immunol, 2018, 200 (5) 1727-1736 PMID: 29358277

Chemical Information

目录号 A12500
Mechanism of action Inhibitor
分子量 868.44
化学分子式 C45H50ClN7O7S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1257044-40-8
Synonyms ABT199; ABT 199; GDC-0199; RG7601
SMILES code CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C
化学名称 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide


ABT-199 is a so-called BH3-mimetic drug, which is designed to block the function of the protein Bcl 2.
Bcl-2 (Cell-free assay) Bcl-xL (Cell-free assay) Bcl-w (Cell-free assay) Mcl-1 (Cell-free assay)
444 nM(Ki)


Solubility (25°C) * In vitro DMSO 100 mg/mL (115.14 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.51 mL 57.57 mL 115.15mL
0.5 mM 2.3 mL 11.51 mL 23.03 mL
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL

*The above data is based on the productmolecular weight 868.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Cat. No.

Product NameSolubility(mg/mL)
A10255ABT-737<1 mg/mL163 mg/mL<1 mg/mL
A10022ABT-263 (Navitoclax)<1 mg/mL195 mg/mL<1 mg/mL
A10665Obatoclax mesylate (GX15-070)<1 mg/mL83 mg/mL<1 mg/mL
A10955TW-37<1 mg/mL115 mg/mL4 mg/mL
A10984VX-765<1 mg/mL102 mg/mL102 mg/mL
A11090PAC-1<1 mg/mL78 mg/mL16 mg/mL
A10491JNJ 26854165<1 mg/mL66 mg/mL2 mg/mL
A11931RITA (NSC 652287)<1 mg/mL115 mg/mL4 mg/mL
A10522Lenalidomide (CC-5013)<1 mg/mL52 mg/mL<1 mg/mL
A10743Pomalidomide (CC-4047)<1 mg/mL55 mg/mL<1 mg/mL
A11163AT-406<1 mg/mL112 mg/mL112 mg/mL
A11002YM15589 mg/mL55 mg/mL6 mg/mL
A10935Tipifarnib (Zarnestra)<1 mg/mL83 mg/mL<1 mg/mL
A10657Nutlin-3<1 mg/mL116 mg/mL116 mg/mL

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.




Similar product(s)

Keywords:购买 ABT-199 (Venetoclax) | ABT-199 (Venetoclax) 供应商 | 订购 ABT-199 (Venetoclax) | ABT-199 (Venetoclax) 价格 | ABT-199 (Venetoclax) 生产商 | 订单 ABT-199 (Venetoclax) | ABT-199 (Venetoclax) 代理商 | 购买 1257044-40-8| 1257044-40-8 供应商 | 订购 1257044-40-8 | 1257044-40-8 价格 | 1257044-40-8 生产商 | 订单 1257044-40-8 | 1257044-40-8 代理商|buy ABT-199 (Venetoclax) | ABT-199 (Venetoclax) Supplier | purchase ABT-199 (Venetoclax) | ABT-199 (Venetoclax) cost | ABT-199 (Venetoclax) manufacturer | order ABT-199 (Venetoclax) | ABT-199 (Venetoclax) distributor | buy 1257044-40-8| 1257044-40-8 Supplier | purchase 1257044-40-8 | 1257044-40-8 cost | 1257044-40-8 manufacturer | order 1257044-40-8 | 1257044-40-8 distributor