ABT-199 (Venetoclax)

目录号: A12500

Bcl-2 inhibitor

ABT-199 (Venetoclax) Chemical Structure

CAS NO. 1257044-40-8

ABT-199 is a so-called BH3-mimetic drug, which is designed to block the function of the protein Bcl 2.

库存: 现货

规格 价格 数量
10 mg
¥ 750.00
50 mg
¥ 1,000.00
100 mg
¥ 1,250.00
10mM * 1mL in DMSO
¥ 700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

ABT-199 is a so-called BH3-mimetic drug, which is designed to block the function of the protein Bcl 2.
Targets
Bcl-2 (Cell-free assay) Bcl-xL (Cell-free assay) Bcl-w (Cell-free assay) Mcl-1 (Cell-free assay)
444 nM(Ki)
In vitro (25°C) DMSO 100 mg/mL (115.14 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.51 mL 57.57 mL 115.15 mL
0.5 mM 2.3 mL 11.51 mL 23.03 mL
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL

*The above data is based on the productmolecular weight 868.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12500
MECHANISM OF ACTION Inhibitor
M. Wt 868.44
Formula C45H50ClN7O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1257044-40-8
Synonyms ABT199; ABT 199; GDC-0199; RG7601
SMILES CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
您还可能对下列产品感兴趣
Keywords:购买 ABT-199 (Venetoclax) | ABT-199 (Venetoclax) 供应商 | 订购 ABT-199 (Venetoclax) | ABT-199 (Venetoclax) 价格 | ABT-199 (Venetoclax) 生产商 | 订单 ABT-199 (Venetoclax) | ABT-199 (Venetoclax) 代理商 | 购买 1257044-40-8| 1257044-40-8 供应商 | 订购 1257044-40-8 | 1257044-40-8 价格 | 1257044-40-8 生产商 | 订单 1257044-40-8 | 1257044-40-8 代理商|buy ABT-199 (Venetoclax) | ABT-199 (Venetoclax) Supplier | purchase ABT-199 (Venetoclax) | ABT-199 (Venetoclax) cost | ABT-199 (Venetoclax) manufacturer | order ABT-199 (Venetoclax) | ABT-199 (Venetoclax) distributor | buy 1257044-40-8| 1257044-40-8 Supplier | purchase 1257044-40-8 | 1257044-40-8 cost | 1257044-40-8 manufacturer | order 1257044-40-8 | 1257044-40-8 distributor
Rewards