ABX-1431
目录号: A18652
MAGL 抑制剂
ABX-1431 是一种高效、选择性强、可口服的中枢神经系统渗透性单酰基甘油酯脂酶（MAGL）抑制剂，其 IC50 为 14 nM。
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生物活性
| Discription | ABX-1431 is a highly potent, selective, and orally available, CNS-penetrant monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 14 nM. |
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产品信息
| 目录号 | A18652 |
|---|---|
| 分子式 | C20H22F9N3O2 |
| 分子量 | 507.39 |
| CAS号 | 1446817-84-0 |
| SMILES | O=C(N1CCN(CC2=CC=C(C(F)(F)F)C=C2N3CCCC3)CC1)OC(C(F)(F)F)C(F)(F)F |
| 其他名称 | ABX-1431; ABX 1431; ABX1431; |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 96 mg/mL (189.2 mM) | |
| Water | Insoluble | ||
| Ethanol | 96 mg/mL (189.2 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.71 mL | 98.54 mL | 197.09 mL |
| 0.5 mM | 3.94 mL | 19.71 mL | 39.42 mL |
| 1 mM | 1.97 mL | 9.85 mL | 19.71 mL |
| 5 mM | 0.39 mL | 1.97 mL | 3.94 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1446817-84-0 | 1446817-84-0 供应商 | 1446817-84-0 花费 | 1446817-84-0 生产商 | 订购 1446817-84-0 | 1446817-84-0 代理商