AC220 (Quizartinib)

Name: AC220 (Quizartinib)
SKU: A10027
Price: 315 CNY
Rating: 5 (4 reviews)

目录号: A10027

FLT3 抑制剂

4 篇发表文献

AC220（Quizartinib）是一种独特的高效和选择性的FLT3抑制剂，其IC50为0.56±0.3 nM，对MC4-11和A375的IC50则大于10 mM。

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Grouped product items
规格	价格	库存
5mg	¥315.00	现货
10mg	¥455.00	现货
25mg	¥630.00	现货
50mg	¥805.00	现货
100mg	¥1,435.00	现货
200mg	¥2,170.00	现货
500mg	¥3,675.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AC220 (Quizartinib)发表的4篇文献

Nicholas R Anderson, .et al. , Leukemia, 2023, Mar;37(3):560-570 PMID: 36550214

N Naganna, .et al. , EBioMedicine, 2019, Jan 24. pii: S2352-3964(19)30012-X PMID: 30686755

Cong Li, .et al. , Mol Cancer Ther., 2015, Feb;14(2):375-83. PMID: 25487917

Yaping Zhang, .et al. , J Pharmacokinet Pharmacodyn., 2014, 41(6): 675-691 PMID: 25326874

生物活性

Discription

AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56±0.3 nM and >10 mM for MC4-11 and A375, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10027
分子式	C29H32N6O4S
分子量	560.7
CAS号	950769-58-1
SMILES	CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	29 mg/mL (51.72 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	15% Captisol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.83 mL	89.17 mL	178.35 mL
0.5 mM	3.57 mL	17.83 mL	35.67 mL
1 mM	1.78 mL	8.92 mL	17.83 mL
5 mM	0.36 mL	1.78 mL	3.57 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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