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AC710 Mesylate

FLT3/KIT/PDGFR??/PDGFR?? 抑制剂

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产品目录号: A16246

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AC710 Mesylate 5mg A16246-5
¥ 1,200.00
AC710 Mesylate 10mg A16246-10
¥ 2,000.00
AC710 Mesylate 50mg A16246-50
¥ 7,600.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AC710 Mesylate is a potent, selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM/1.0 nM/1.3 nM/1.0 nM for FLT3/KIT/PDGFRα/PDGFRβ respectively.

AC710 Mesylate

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Chemical Information

目录号 A16246
Mechanism of action Inhibitor
分子量 658.81
化学分子式 C32H46N6O7S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1351522-05-8
Synonyms AC 710 Mesylate, AC-710 Mesylate
SMILES code CCN1C(CC(CC1(C)C)OC2=CN=C(C=C2)C(=O)NC3=CC=C(C=C3)NC(=O)NC4=NOC(=C4)C(C)(C)C)(C)C.CS(=O)(=O)O
化学名称 N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxypyridine-2-carboxamide;methanesulfonic acid

生物活性

Description
AC710 Mesylate is a potent, selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM/1.0 nM/1.3 nM/1.0 nM for FLT3/KIT/PDGFRα/PDGFRβ respectively.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.18 mL 75.89 mL 151.79mL
0.5 mM 3.04 mL 15.18 mL 30.36 mL
1 mM 1.52 mL 7.59 mL 15.18 mL
5 mM 0.3 mL 1.52 mL 3.04 mL

*The above data is based on the productmolecular weight 658.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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