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Acadesine (Aicar,NSC 105823)

促销

AMPK activator

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产品目录号: A10028

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Acadesine 50mg A10028-50
¥ 500.00
Acadesine 100mg A10028-100
¥ 700.00
Acadesine 200mg A10028-200
¥ 1,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Acadesine is a selective activator of AMPK in both hepatocytes and adipocytes.

Acadesine (Aicar,NSC 105823)

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Acadesine (Aicar,NSC 105823) 发表的文献 (2)
  • R. Lim, .et al. Activation of AMPK in human fetal membranes alleviates infection-induced expression of pro-inflammatory and pro-labour mediators., Placenta, 2015, Apr;36(4):454-62 PMID: 25659498
  • Stella Liong, .et al. Activation of AMPK improves inflammation and insulin resistance in adipose tissue and skeletal muscle from pregnant women., J Physiol Biochem, 2015, Dec;71(4):703-17 PMID: 26407807

Chemical Information

目录号 A10028
Mechanism of action Activator
分子量 258.2
化学分子式 C9H14N4O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 2627-69-2
Synonyms AICAR, AICA-riboside, NSC-105823, NSC105823
SMILES code C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N)C(=O)N
化学名称 5-​amino-​1-​β-​D-​ribofuranosyl-​1H-​imidazole-​4-​carboxamide

生物活性

Description

Acadesine is a selective activator of AMPK in both hepatocytes and adipocytes.

Targets
AMPK (Cell-free assay) AMPKK (Cell-free assay)

溶解性

Solubility (25°C)* In vitro DMSO 2 mg/mL (7.74 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.73 mL 193.65 mL 387.3mL
0.5 mM 7.75 mL 38.73 mL 77.46 mL
1 mM 3.87 mL 19.36 mL 38.73 mL
5 mM 0.77 mL 3.87 mL 7.75 mL

*The above data is based on the productmolecular weight 258.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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