Acasunlimab (GEN1046) is a bispecific antibody designed to simultaneously target PD-L1 and 4-1BB. This innovative therapeutic agent facilitates the enhancement of T-cell and NK-cell activity via conditional stimulation of 4-1BB, while consistently inhibiting the PD-1/PD-L1 axis. Acasunlimab is primarily utilized in cancer research, focusing on its potential to modulate immune checkpoint pathways and improve antitumor responses.
Acasunlimab (GEN1046) is a bispecific antibody designed to simultaneously target PD-L1 and 4-1BB. This innovative therapeutic agent facilitates the enhancement of T-cell and NK-cell activity via conditional stimulation of 4-1BB, while consistently inhibiting the PD-1/PD-L1 axis. Acasunlimab is primarily utilized in cancer research, focusing on its potential to modulate immune checkpoint pathways and improve antitumor responses.
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